Organelle detection and tracking

I worked with various groups at the University of Exeter to create organelle detection, tracking, and analysis pipelines.

These involved a range of cellular organelles including Endosomes, Peroxisomes¹, and Mitochondria².

References

¹

Costello, J.L., Castro, I.G., Hacker, C., Schrader, T.A., Metz, J., Zeuschner, D., Azadi, A.S., Godinho, L.F., Costina, V., Findeisen, P. and Manner, A., 2017. ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER. Journal of Cell Biology, 216(2), pp.331-342.

²

Barel, O., Malicdan, M.C.V., Ben-Zeev, B., Kandel, J., Pri-Chen, H., Stephen, J., Castro, I.G., Metz, J., Atawa, O., Moshkovitz, S. and Ganelin, E., 2017. Deleterious variants in TRAK1 disrupt mitochondrial movement and cause fatal encephalopathy. Brain, 140(3), pp.568-581.